Application
Phenylalanine-4′-azobenzene HCl (AzoF) is a phenylalanine derivative with an azo bond that isomerizes upon UV irradiation from its E isomer to its Z isomer and reverts back at light above 400 nm. When incorporated into proteins or chemical probes, this reversibility is utilized as a photoswitch with spatial and temporal regulation within biological systems.
Other Notes
Light Regulation of Enzyme Allostery through Photo-responsive Unnatural Amino AcidsPhotochemical control of enzymes using photoresponsive compounds on the basis of the interaction mechanismPhotochemical regulation of the activity of an endonuclease BamHI using an azobenzene moiety incorporated site-selectively into the dimer interface
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